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Karczmar, Gregory
One or more keywords matched the following properties of Karczmar, Gregory
PropertyValue
keywords Breast cancer screening with MRI
keywords Prostate cancer screening with MRI
keywords Screening iof underserved groups
keywords Quantitative MRI
overview I have developed new approaches to functional and anatomic magnetic resonance imaging for over 30 years. I’ve applied these methods to improve detection and accurate diagnosis of cancer, and monitor cancer response to therapy. I am the Director of Magnetic Resonance Imaging Research at the University of Chicago, and Co-Director of the Advanced Imaging Program of the University of Chicago Comprehensive Cancer center. I’ve collaborated with our outstanding mammographic group and medical physics colleagues for many years to build internationally recognized research program in quantitative breast cancer MR imaging – which parallels and compliments a leading clinical program in breast cancer diagnosis and management. Similarly, I’ve collaborated with Dr. Oto and others to develop a leading translational research program focused on improving prostate cancer screening with MRI, and using MRI to guide therapye. With these collaborators, I’ve made pioneering contributions to MRI methods that improve prostate and breast cancer diagnosis and treatment. My research includes use of pre-clinical methods for breast and prostate cancer to improve understanding of cancer biology and guide the development of improved clinical methods.
One or more keywords matched the following items that are connected to Karczmar, Gregory
Item TypeName
Concept Mass Screening
Concept Prostatic Neoplasms
Academic Article Uptake of a superparamagnetic contrast agent imaged by MR with high spectral and spatial resolution.
Academic Article Differentiation of nonmetastatic and metastatic rodent prostate tumors with high spectral and spatial resolution MRI.
Academic Article A new method for imaging perfusion and contrast extraction fraction: input functions derived from reference tissues.
Academic Article Imaging spin probe distribution in the tumor of a living mouse with 250 MHz EPR: correlation with BOLD MRI.
Academic Article Spectrally inhomogeneous effects of contrast agents in breast lesion detected by high spectral and spatial resolution MRI.
Academic Article MRI measurements correctly predict the relative effects of tumor oxygenating agents on hypoxic fraction in rodent BA1112 tumors.
Academic Article MRI of the tumor microenvironment.
Academic Article Functional and anatomic imaging of tumor vasculature: high-resolution MR spectroscopic imaging combined with a superparamagnetic contrast agent.
Academic Article Structure of the water resonance in small voxels in rat brain detected with high spectral and spatial resolution MRI.
Academic Article Effect of carbogen on tumor oxygenation: combined fluorine-19 and proton MRI measurements.
Academic Article Quantitative tumor oxymetric images from 4D electron paramagnetic resonance imaging (EPRI): methodology and comparison with blood oxygen level-dependent (BOLD) MRI.
Academic Article Using high spectral and spatial resolution bold MRI to choose the optimal oxygenating treatment for individual cancer patients.
Academic Article Semiquantitative analysis of dynamic contrast enhanced MRI in cancer patients: Variability and changes in tumor tissue over time.
Academic Article Fourier components of inhomogeneously broadened water resonances in breast: a new source of MRI contrast.
Academic Article Multi-slice DCE-MRI data using P760 distinguishes between metastatic and non-metastatic rodent prostate tumors.
Academic Article High spectral and spatial resolution MRI of breast lesions: preliminary clinical experience.
Academic Article MRI of perfluorocarbon emulsion kinetics in rodent mammary tumours.
Academic Article Fat suppression with spectrally selective inversion vs. high spectral and spatial resolution MRI of breast lesions: qualitative and quantitative comparisons.
Academic Article Comparison and evaluation of mouse cardiac MRI acquired with open birdcage, single loop surface and volume birdcage coils.
Academic Article Differentiation between benign and malignant breast lesions detected by bilateral dynamic contrast-enhanced MRI: a sensitivity and specificity study.
Academic Article Quantitative analysis of water proton spectral lineshape: a novel source of contrast in MRI.
Academic Article New model for analysis of dynamic contrast-enhanced MRI data distinguishes metastatic from nonmetastatic transplanted rodent prostate tumors.
Academic Article Detection of in situ mammary cancer in a transgenic mouse model: in vitro and in vivo MRI studies demonstrate histopathologic correlation.
Academic Article Estimating the arterial input function using two reference tissues in dynamic contrast-enhanced MRI studies: fundamental concepts and simulations.
Academic Article A new approach to analysis of the impulse response function (IRF) in dynamic contrast-enhanced MRI (DCEMRI): a simulation study.
Academic Article Reproducibility assessment of a multiple reference tissue method for quantitative dynamic contrast enhanced-MRI analysis.
Academic Article Kinetic curves of malignant lesions are not consistent across MRI systems: need for improved standardization of breast dynamic contrast-enhanced MRI acquisition.
Academic Article Comparison of high-resolution echo-planar spectroscopic imaging with conventional MR imaging of prostate tumors in mice.
Academic Article Characterization of response to radiation mediated gene therapy by means of multimodality imaging.
Academic Article Quantitative analysis of dynamic contrast enhanced MRI for assessment of bowel inflammation in Crohn's disease pilot study.
Academic Article Clinical implementation of a multislice high spectral and spatial resolution-based MRI sequence to achieve unilateral full-breast coverage.
Academic Article The influence of temporal resolution in determining pharmacokinetic parameters from DCE-MRI data.
Academic Article Prostate cancer: differentiation of central gland cancer from benign prostatic hyperplasia by using diffusion-weighted and dynamic contrast-enhanced MR imaging.
Academic Article Characterizing early contrast uptake of ductal carcinoma in situ with high temporal resolution dynamic contrast-enhanced MRI of the breast: a pilot study.
Academic Article Diagnosis of suspicious breast lesions using an empirical mathematical model for dynamic contrast-enhanced MRI.
Academic Article Normal parenchymal enhancement patterns in women undergoing MR screening of the breast.
Academic Article High-resolution MRI of excised human prostate specimens acquired with 9.4T in detection and identification of cancers: validation of a technique.
Academic Article Diffusion-weighted and dynamic contrast-enhanced MRI of prostate cancer: correlation of quantitative MR parameters with Gleason score and tumor angiogenesis.
Academic Article Can DCEMRI assess the effect of green tea on the angiogenic properties of rodent prostate tumors?
Academic Article Comparison of quantitative parameters in cervix cancer measured by dynamic contrast-enhanced MRI and CT.
Academic Article In vivo MRI of early stage mammary cancers and the normal mouse mammary gland.
Academic Article Comparing post-operative human breast specimen radiograph and MRI in lesion margin and volume assessment.
Academic Article Non-contrast enhanced MRI for evaluation of breast lesions: comparison of non-contrast enhanced high spectral and spatial resolution (HiSS) images versus contrast enhanced fat-suppressed images.
Academic Article Dynamic contrast-enhanced MR imaging findings of bone metastasis in patients with prostate cancer.
Academic Article The use of a reference tissue arterial input function with low-temporal-resolution DCE-MRI data.
Academic Article Spectrally inhomogeneous BOLD contrast changes detected in rodent tumors with high spectral and spatial resolution MRI.
Academic Article Comparison of 31P MRS and 1H MRI at 1.5 and 2.0 T.
Academic Article High spectral and spatial resolution MRI of age-related changes in murine prostate.
Academic Article Sensitivity to tumor microvasculature without contrast agents in high spectral and spatial resolution MR images.
Academic Article Hyperthermically induced changes in high spectral and spatial resolution MR images of tumor tissue--a pilot study.
Academic Article MR imaging-guided focal laser ablation for prostate cancer: phase I trial.
Academic Article Monitoring anti-angiogenic therapy in colorectal cancer murine model using dynamic contrast-enhanced MRI: comparing pixel-by-pixel with region of interest analysis.
Academic Article High resolution 3D MRI of mouse mammary glands with intra-ductal injection of contrast media.
Academic Article X-ray fluorescence microscopy demonstrates preferential accumulation of a vanadium-based magnetic resonance imaging contrast agent in murine colonic tumors.
Academic Article Hybrid multidimensional T(2) and diffusion-weighted MRI for prostate cancer detection.
Academic Article Potential of computer-aided diagnosis of high spectral and spatial resolution (HiSS) MRI in the classification of breast lesions.
Academic Article Comparison of dynamic contrast-enhanced MRI parameters of breast lesions at 1.5 and 3.0?T: a pilot study.
Academic Article Prostate volumes derived from MRI and volume-adjusted serum prostate-specific antigen: correlation with Gleason score of prostate cancer.
Academic Article MRI of neonatal necrotizing enterocolitis in a rodent model.
Academic Article Dynamic contrast-enhanced MR imaging features of the normal central zone of the prostate.
Academic Article Quantitative evaluation of internal marks made using MRgFUS as seen on MRI, CT, US, and digital color images - a pilot study.
Academic Article High-resolution diffusion-weighted imaging of the prostate.
Academic Article Residual analysis of the water resonance signal in breast lesions imaged with high spectral and spatial resolution (HiSS) MRI: a pilot study.
Academic Article MRI accurately identifies early murine mammary cancers and reliably differentiates between in situ and invasive cancer: correlation of MRI with histology.
Academic Article Short-term reproducibility of apparent diffusion coefficient estimated from diffusion-weighted MRI of the prostate.
Academic Article Arterial input functions (AIFs) measured directly from arteries with low and standard doses of contrast agent, and AIFs derived from reference tissues.
Academic Article Benign Conditions That Mimic Prostate Carcinoma: MR Imaging Features with Histopathologic Correlation.
Academic Article Ultrafast Bilateral DCE-MRI of the Breast with Conventional Fourier Sampling: Preliminary Evaluation of Semi-quantitative Analysis.
Academic Article Pilot Study of the Use of Hybrid Multidimensional T2-Weighted Imaging-DWI for the Diagnosis of Prostate Cancer and Evaluation of Gleason Score.
Academic Article Kinetic Analysis of Benign and Malignant Breast Lesions With Ultrafast Dynamic Contrast-Enhanced MRI: Comparison With Standard Kinetic Assessment.
Academic Article Breast density estimation from high spectral and spatial resolution MRI.
Academic Article Fast bilateral breast coverage with high spectral and spatial resolution (HiSS) MRI at 3T.
Academic Article Value of breast MRI for patients with a biopsy showing atypical ductal hyperplasia (ADH).
Academic Article MRI ductography of contrast agent distribution and leakage in normal mouse mammary ducts and ducts with in situ cancer.
Academic Article MRI reveals increased tumorigenesis following high fat feeding in a mouse model of triple-negative breast cancer.
Academic Article Multiparametric MRI Features and Pathologic Outcome of Wedge-Shaped Lesions in the Peripheral Zone on T2-Weighted Images of the Prostate.
Academic Article Performance of T2 Maps in the Detection of Prostate Cancer.
Academic Article Diagnosis of Prostate Cancer with Noninvasive Estimation of Prostate Tissue Composition by Using Hybrid Multidimensional MR Imaging: A Feasibility Study.
Academic Article Performance of Ultrafast DCE-MRI for Diagnosis of Prostate Cancer.
Academic Article Feasibility of Dynamic Contrast-Enhanced Magnetic Resonance Imaging Using Low-Dose Gadolinium: Comparative Performance With Standard Dose in Prostate Cancer Diagnosis.
Academic Article MRI Findings After MRI-Guided Focal Laser Ablation of Prostate Cancer.
Academic Article Ultrafast Dynamic Contrast-Enhanced Breast MRI: Kinetic Curve Assessment Using Empirical Mathematical Model Validated with Histological Microvessel Density.
Academic Article Dynamic field-of-view imaging to increase temporal resolution in the early phase of contrast media uptake in breast DCE-MRI: A feasibility study.
Academic Article Quantitative analysis of vascular properties derived from ultrafast DCE-MRI to discriminate malignant and benign breast tumors.
Academic Article Comparison of arterial input functions measured from ultra-fast dynamic contrast enhanced MRI and dynamic contrast enhanced computed tomography in prostate cancer patients.
Academic Article Comparison of region-of-interest-averaged and pixel-averaged analysis of DCE-MRI data based on simulations and pre-clinical experiments.
Academic Article Fast Temporal Resolution Dynamic Contrast-Enhanced MRI: Histogram Analysis Versus Visual Analysis for Differentiating Benign and Malignant Breast Lesions.
Academic Article Evaluation of Focal Laser Ablation of Prostate Cancer Using High Spectral and Spatial Resolution Imaging: A Pilot Study.
Academic Article Intensive Surveillance with Biannual Dynamic Contrast-Enhanced Magnetic Resonance Imaging Downstages Breast Cancer in BRCA1 Mutation Carriers.
Academic Article Comparison of T2-Weighted Imaging, DWI, and Dynamic Contrast-Enhanced MRI for Calculation of Prostate Cancer Index Lesion Volume: Correlation With Whole-Mount Pathology.
Academic Article Revisiting quantitative multi-parametric MRI of benign prostatic hyperplasia and its differentiation from transition zone cancer.
Academic Article Diagnosis of Prostate Cancer by Use of MRI-Derived Quantitative Risk Maps: A Feasibility Study.
Academic Article A compact solution for estimation of physiological parameters from ultrafast prostate dynamic contrast enhanced MRI.
Academic Article Use of Indicator Dilution Principle to Evaluate Accuracy of Arterial Input Function Measured With Low-Dose Ultrafast Prostate Dynamic Contrast-Enhanced MRI.
Academic Article Low-dose imaging technique (LITE) MRI: initial experience in breast imaging.
Academic Article Effect of Echo Times on Prostate Cancer Detection on T2-Weighted Images.
Academic Article T2*-weighted MRI as a non-contrast-enhanced method for assessment of focal laser ablation zone extent in prostate cancer thermotherapy.
Academic Article Signal intensity form of the Tofts model for quantitative analysis of prostate dynamic contrast enhanced MRI data.
Academic Article Comparison of DCE-MRI of murine model cancers with a low dose and high dose of contrast agent.
Academic Article Design, evaluation and initial imaging results of a PET insert based on strip-line readout for simultaneous PET/MRI.
Academic Article Improving Tumor Hypoxia Location in 18F-Misonidazole PET with Dynamic Contrast-enhanced MRI Using Quantitative Electron Paramagnetic Resonance Partial Oxygen Pressure Images.
Academic Article High spectral and spatial resolution MRI of prostate cancer: a pilot study.
Grant MR Virtual Pathology of the Prostate
Academic Article An in silico validation framework for quantitative DCE-MRI techniques based on a dynamic digital phantom.
Academic Article Effectiveness of Dynamic Contrast Enhanced MRI with a Split Dose of Gadoterate Meglumine for Detection of Prostate Cancer.
Academic Article Can Pre-treatment Quantitative Multi-parametric MRI Predict the Outcome of Radiotherapy in Patients with Prostate Cancer?
Academic Article Enhancement-constrained acceleration: A robust reconstruction framework in breast DCE-MRI.
Academic Article Validation of Prostate Tissue Composition by Using Hybrid Multidimensional MRI: Correlation with Histologic Findings.
Academic Article Histological validation of prostate tissue composition measurement using hybrid multi-dimensional MRI: agreement with pathologists' measures.
Academic Article Physically implausible signals as a quantitative quality assessment metric in prostate diffusion-weighted MR imaging.
Academic Article Directional and inter-acquisition variability in diffusion-weighted imaging and editing for restricted diffusion.
Academic Article Comparing Radiologist Performance in Diagnosing Clinically Significant Prostate Cancer with Multiparametric versus Hybrid Multidimensional MRI.
Academic Article Parametric maps of spatial two-tissue compartment model for prostate dynamic contrast enhanced MRI - comparison with the standard Tofts model in the diagnosis of prostate cancer.
Academic Article Comparison of synthesized and acquired high b -value diffusion-weighted MRI for detection of prostate cancer.
Academic Article Standardization of Breast Dynamic Contrast-enhanced MRI Signal with Application to the Assessment of Background Parenchymal Enhancement Rate.
Grant Dynamic Spatial and Spectral, Contrast Enhanced MRI of *
Grant Quantitative MRI for Predicting Response of Breast Cancer to Neoadjuvant Therapy
Grant Detection of prostate Cancer Specific Signals with Hybrid Multi-Dimensional MRI
Grant Microvessel Density With High Spectral/Spatial MRI
Grant Assessment of Breast Cancer Risk with High Spectral and Spatial Resolution MRI
Grant Microvessel Density With High Spectral/Spatial MRI
Grant High Spectral &Spatial Resolution MRI of Rodent Tumors
Grant 3T MRI Scanner for multidisciplinary imaging and image-guided therapy
Grant Fast Spectroscopic MR Imaging of Breast Cancer
Grant MRI of Early Non-invasive Rodent Mammary Cancers
Grant High Spectral/Spatial Resolution Imaging Breast Cancer
Grant Breast Cancer Screening with Quantitative Ultra-Fast DCEMRI and Clinical Risk Assessment
Grant UPGRADE FOR 4.7 TESLA MR SCANNER
Grant EFFECTS OF RADIOSENSITIZERS MEASURED BY MRI
Grant In Vivo Measurements of Physiologically-evoked Neuronal Currents
Grant Quantitative DCEMRI of Prostate Cancer Correlation with Gold Standards
Grant A 7 Tesla magnet for the University of Chicago MRI research scanner
Academic Article An Interactive App with Multi-parametric MRI - Whole-Mount Histology Correlation for Enhanced Prostate MRI Training of Radiology Residents.
Academic Article Characterization of Effects of Compressed Sensing on High Spectral and Spatial Resolution (HiSS) MRI with Comparison to SENSE.
Academic Article Improving reader accuracy and specificity with the addition of hybrid multidimensional-MRI to multiparametric-MRI in diagnosing clinically significant prostate cancers.
Academic Article Pharmacokinetic Analysis of Enhancement-Constrained Acceleration (ECA) reconstruction-based high temporal resolution breast DCE-MRI.
Academic Article Parametric maps of spatial two-tissue compartment model for prostate dynamic contrast enhanced MRI - comparison with the standard tofts model in the diagnosis of prostate cancer.
Academic Article Four-quadrant vector mapping of hybrid multidimensional MRI data for the diagnosis of prostate cancer.
Academic Article Bilateral asymmetry of quantitative parenchymal kinetics at ultrafast DCE-MRI predict response to neoadjuvant chemotherapy in patients with HER2+ breast cancer.
Academic Article Multi-model sequential analysis of MRI data for microstructure prediction in heterogeneous tissue.
Academic Article Prostate Cancers Invisible on Multiparametric MRI: Pathologic Features in Correlation with Whole-Mount Prostatectomy.
Academic Article Self-supervised multicontrast super-resolution for diffusion-weighted prostate MRI.
Academic Article Systematic evaluation of MRI-based characterization of tumor-associated vascular morphology and hemodynamics via a dynamic digital phantom.
Search Criteria
  • Prostate cancer
  • screening
  • MRI